Sure, if you are an attention hog!
Whether class size matter depends on what type of learning experience you want to gain in college. Small class sizes can provide personal attention from professors, more interactive classroom discussions, challenging course materials, and opportunities to dig deeper in a particular topic. Also, small class sizes are often founded at liberal arts colleges rather than national and private universities. Hence, the choice between small and large class sizes might influence your decision to attend a Big 10 university versus a New England liberal college.
Admittedly, I am biased toward smaller class size as someone who went to a liberal college where there was two students in one of my advanced economics classes. However, small class size do have some disadvantages. First, smaller classes may have less diversity of ideas and experiences. Second, smaller classes are often dictated by the classroom discussion, which can feel less structured. Larger class settings are usually more guided because it would be too unwieldy to allow the class steer off track. Third, smaller class sizes allow very little room for you to come unprepared and unnoticed. If you do not enjoy being called upon or expected to contribute, a larger class size may take this pressure off your shoulders.
Overall, class size is very critical and it is often overlook in the admission process. However, it can play a major factor in how enjoyable the learning experience is and how you succeed in college.